Systematic review or meta-analysis?
A systematic review answers a defined research question by collecting and summarizing all empirical evidence that fits pre-specified eligibility criteria.
A meta-analysis is the use of statistical methods to summarize the results of these studies.
Systematic reviews, just like other research articles, can be of varying quality. They are a significant piece of work (the Centre for Reviews and Dissemination at York estimates that a team will take 9-24 months), and to be useful to other researchers and practitioners they should have:
- clearly stated objectives with pre-defined eligibility criteria for studies
- explicit, reproducible methodology
- a systematic search that attempts to identify all studies
- assessment of the validity of the findings of the included studies (e.g. risk of bias)
- systematic presentation, and synthesis, of the characteristics and findings of the included studies
Not all systematic reviews contain meta-analysis.
Meta-analysis is the use of statistical methods to summarize the results of independent studies. By combining information from all relevant studies, meta-analysis can provide more precise estimates of the effects of health care than those derived from the individual studies included within a review. More information on meta-analyses can be found in Cochrane Handbook, Chapter 9.
A meta-analysis goes beyond critique and integration and conducts secondary statistical analysis on the outcomes of similar studies. It is a systematic review that uses quantitative methods to synthesize and summarize the results.
An advantage of a meta-analysis is the ability to be completely objective in evaluating research findings. Not all topics, however, have sufficient research evidence to allow a meta-analysis to be conducted. In that case, an integrative review is an appropriate strategy.